Archive for October, 2008

Heart Advisor - Genes provide key to dosing formulas for blood thinner

Wednesday, October 29th, 2008

Getting the right dose of the common stroke-prevention blood thinner warfarin (Coumadin) should become easier thanks to researchers who developed dosing formulas based on variations in two key genes, VKORC1 and …

HealthDay - New Anti-Clotting Pill Works Well in Trials

Sunday, October 26th, 2008

A new anti-clotting drug that could be one of the long-sought alternatives to commonly used blood thinners has performed well in hip and knee replacement patients, physicians report.
The drug, rivaroxaban, was more effective at reducing potentially fatal blood clots than heparin, with no increas…

Medical Laboratory Observer - Hitting the target with antithrombotic therapy

Saturday, October 25th, 2008

Every day, millions of women take a blood thinner called warfarin (Coumadin) to reduce their risk of stroke. It’s commonly prescribed for people with atrial fibrillation (AF), an abnormal heart rhythm that causes the upper chambers of the heart (atria) to quiver ineffectively rather than contract normally, allowing blood to pool and potentially form clots. Although warfarin can cut the risk of stroke by more than 60 percent, it can also increase the chance of hem…

HealthDay - Finding May Allow Some Women to Stop Blood Thinners

Thursday, October 23rd, 2008

A new study identifies some women — but not men — who might be able to stop taking blood-thinning medication for the clotting condition called venous thromboembolism.
Current guidelines call for indefinite use of a clot-preventing drug, most often warfarin (Coumadin), for …

Keystone Therapeutics, Inc. Selected to Provide DoseResponse

Sunday, October 19th, 2008

Keystone Therapeutics, Inc. has signed an agreement with The Cleveland Clinic Health System of Cleveland, Ohio to provide their community hospital-based coumadin clinics with DoseResponse anticoagulatio…

HealthDay - Genetic Test Approved for Sensitivity to Blood Thinner

Friday, October 17th, 2008

The U.S. Food and Drug Administration has approved a genetic test to help doctors determine if a person is highly sensitive to the blood-thinning drug Coumadin (generic name: warfarin), increasing the risk of excessive bleeding.
About one-third of people who receive the drug, commonly prescribed to prevent dangerous blood clots, metabolize it differently, the FDA said. Two gene variants believed responsible for the unusual response are detected by the new test, produced by Northbrook, Ill.-b…

Environmental Nutrition - Ginseng may reduce action of Coumadin

Monday, October 13th, 2008

Taking the popular herb ginseng may undermine the blood-thinning action of the prescription drug warfarin (Coumadin). That’s the conclusion of a recent four-week study conducted at the Tang Center for Herbal Medicine Research at the University of Chicago.
Surprising Results. Of the 20 healthy men and women in the study, half were given warfarin for three days before and three days after they were given ginseng. The othe…

Saturday Evening Post - Clot on ICD raises questions

Monday, October 13th, 2008

Q: My heart went out of rhythm on November 1, 2007, and two weeks later I had a stroke. They were going to use my ICD to get the heart back in rhythm, but when they checked for a clot in the heart, they found one on the terminal of the ICD. For the past month I took Coumadin followed by shots of Lovenox. The clot is still on the terminal. Do you have a…

Detailed Information on Embolism

Saturday, October 11th, 2008

PE may arise from deep vein thrombosis throughout the body. Fatal PE is often a result of thrombus emanating from the sub-axillary or veins (deep veins in the arm or shoulder) or in the veins of the pelvis. Several fac…

Environmental Nutrition - Coumadin caution: limit cranberry juice

Wednesday, October 8th, 2008

If you take the blood thinner warfarin (Coumadin), the United Kingdom’s Committee on Safety of Medicines warns that you should limit or avoid drinking cranberry juice.
Clotting Concerns. The agency–similar to the U.S. Food and Drug Administration–reports five cases since 1999 in which combining the drug and the juice c…